This project investigates the spatial conformation of the chromatin in the nucleus of pig muscle cells during late development.
Using High-throughput Chromosome Conformation Capture (in situ Hi-C), we identified, characterized and compared genomic interaction matrices from muscle samples at two different stages (90 and 110 days post gestation, with 3 biological replicates per stage).
Information about the biological material that was used in this study is available:
Sequencing data generated by in situ Hi-C experiments are available:
Results from the computational data analysis are available at the INRAE Data Portail under the doi doi:10.15454/DOMEHB. This includes:
A code repository with documented scripts for data visualization and analysis has been made available at the INRAE Forge: pig3Dgenome. This includes:
If you use this resource, please cite the following article
Marti-Marimon M, Vialaneix N, Lahbib-Mansais Y, Zytnicki M, Camut S, Robelin D, Yerle-Bouissou M and Foissac S (2021) Major Reorganization of Chromosome Conformation During Muscle Development in Pig. Front. Genet. 12:748239. doi: 10.3389/fgene.2021.748239