Project overview

As part of the FAANG action (Functional Annotation of ANimal Genomes), the FR-AgENCODE project aims at improving the genomic annotation of 4 livestock species:

  • cattle (Bos taurus)
  • goat (Capra hircus)
  • chicken (Gallus gallus)
  • pig (Sus scrofa)

This is achieved by performing molecular assays on tissue dissociated cells (liver) and on sorted primary cells (CD4+ and CD8+ T lymphocytes) from 2 males and 2 females of each species. These assays include RNA-seq, ATAC-seq and Hi-C to characterize the transcriptome, the chromatin accessibility and the genome 3D topology in these cells, respectively.

Founded by INRAE (2014-17), the project was coordinated by Elisabetta Giuffra and Sylvain Foissac.

INRAE
French National Institute for Agricultural Research

INSERM
French National Institute for Biomedical Research and Health

Institut Agro
Institute for Agricultural Research

FAANG
Functional Annotation of Animal Genomes