Project overview

As part of the FAANG action (Functional Annotation of ANimal Genomes), the FR-AgENCODE project aims at improving the genomic annotation of 4 livestock species:

  • cattle (Bos taurus)
  • goat (Capra hircus)
  • chicken (Gallus gallus)
  • pig (Sus scrofa)

This is achieved by performing molecular assays on tissue dissociated cells (liver) and on sorted primary cells (CD4+ and CD8+ T lymphocytes) from 2 males and 2 females of each species. These assays include RNA-seq, ATAC-seq and Hi-C to characterize the transcriptome, the chromatin accessibility and the genome 3D topology in these cells, respectively.

Founded by INRAE (2014-17), the project was coordinated by Elisabetta Giuffra and Sylvain Foissac.

French National Institute for Agricultural Research

Functional Annotation of Animal Genomes